Structured Summary
Abstract
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H12N2
- Molecular Weight
- 160.22 g/mol
- CAS Registry No.
- 59-98-3
- IUPAC Name
- 2-benzyl-4,5-dihydro-1H-imidazole
- InChIKey
- JIVZKJJQOZQXQB-UHFFFAOYSA-N
- SMILES
- C1CN=C(N1)CC2=CC=CC=C2
- MeSH Unique ID
- D014043
- Source
- PubChem CID 5504
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Benzalolin
- Divascol
- Pridazole
- Priscol
- Priscoline
- Tolazoline Hydrochloride
- Tolazoline Monohydrochloride
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Tolazoline. Medical Subject Headings (MeSH). 2026. Unique ID D014043. http://id.nlm.nih.gov/mesh/2026/D014043
- Tolazoline. In: Wikipedia. https://en.wikipedia.org/wiki/Tolazoline
- Tolazoline. In: Wikidata. https://www.wikidata.org/wiki/Q413772
- Tolazoline. In: PubChem Compound. CID 5504. https://pubchem.ncbi.nlm.nih.gov/compound/5504