Chemicals and Drugs

Toll-Like Receptors

A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

6 entry terms
  • Receptors, Toll-Like
  • Toll-Like Receptor
  • Receptor, Toll-Like
  • Receptors, Toll Like
  • Toll Like Receptor
  • Toll Like Receptors

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

2006(1998)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QW 569

AMA Style

References

  1. National Library of Medicine. Toll-Like Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D051193. http://id.nlm.nih.gov/mesh/2026/D051193
  2. Toll-Like Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Toll-like_receptor
  3. Toll-Like Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q408004