Structured Summary
Abstract
A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
Chemical Identity
Chemical Information
- Molecular Formula
- C19H22ClN5O
- Molecular Weight
- 371.9 g/mol
- CAS Registry No.
- 19794-93-5
- IUPAC Name
- 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
- InChIKey
- PHLBKPHSAVXXEF-UHFFFAOYSA-N
- SMILES
- C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl
- MeSH Unique ID
- D014196
- Source
- PubChem CID 5533
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
28 entry terms
- Tradozone
- AF-1161
- Apo-Trazodone
- Deprax
- Desyrel
- Gen-Trazodone
- Molipaxin
- Novo-Trazodone
- Nu-Trazodone
- PMS-Trazodone
- Ratio-Trazodone
- Thombran
- Trazodon Hexal
- Trazodon-Neuraxpharm
- Trazodone Hydrochloride
- Trazon
- Trittico
- AF 1161
- AF1161
- Apo Trazodone
- Gen Trazodone
- Novo Trazodone
- Nu Trazodone
- PMS Trazodone
- Ratio Trazodone
- RatioTrazodone
- Trazodon Neuraxpharm
- TrazodonNeuraxpharm
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
86(75); was see under PIPERAZINES 1975-85
MeSH Record
Previous Indexing
- Piperazines (1971-1974)
- Pyridines (1971-1974)
- Triazoles (1971-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Trazodone. Medical Subject Headings (MeSH). 2026. Unique ID D014196. http://id.nlm.nih.gov/mesh/2026/D014196
- Trazodone. In: Wikipedia. https://en.wikipedia.org/wiki/Trazodone
- Trazodone. In: Wikidata. https://www.wikidata.org/wiki/Q411457
- Trazodone. In: PubChem Compound. CID 5533. https://pubchem.ncbi.nlm.nih.gov/compound/5533