Chemicals and Drugs

Trifluperidol

A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in the treatment of PSYCHOSES including MANIA and SCHIZOPHRENIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p621)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in the treatment of PSYCHOSES including MANIA and SCHIZOPHRENIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p621)

Chemical Identity

Chemical Information

Molecular Formula
C22H23F4NO2
Molecular Weight
409.4 g/mol
CAS Registry No.
749-13-3
IUPAC Name
1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]butan-1-one
InChIKey
GPMXUUPHFNMNDH-UHFFFAOYSA-N
SMILES
C1CN(CCC1(C2=CC(=CC=C2)C(F)(F)F)O)CCCC(=O)C3=CC=C(C=C3)F
MeSH Unique ID
D014272
Source
PubChem CID 5567

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Trisedil

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

72(65)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Trifluperidol. Medical Subject Headings (MeSH). 2026. Unique ID D014272. http://id.nlm.nih.gov/mesh/2026/D014272
  2. Trifluperidol. In: Wikipedia. https://en.wikipedia.org/wiki/Trifluperidol
  3. Trifluperidol. In: Wikidata. https://www.wikidata.org/wiki/Q4463264
  4. Trifluperidol. In: PubChem Compound. CID 5567. https://pubchem.ncbi.nlm.nih.gov/compound/5567