Chemicals and Drugs

Tripelennamine

A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

Chemical Identity

Chemical Information

Molecular Formula
C16H21N3
Molecular Weight
255.36 g/mol
CAS Registry No.
91-81-6
IUPAC Name
N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
InChIKey
UFLGIAIHIAPJJC-UHFFFAOYSA-N
SMILES
CN(C)CCN(CC1=CC=CC=C1)C2=CC=CC=N2
MeSH Unique ID
D014309
Source
PubChem CID 5587

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Azaron
  • Histantin
  • Pyribenzamine
  • Tripelennamine Citrate
  • Tripelennamine Citrate (1:1)
  • Tripelennamine Hydrochloride
  • Tripelennamine Maleate
  • Tripelennamine Maleate (1:1)
  • Tripelennamine Monohydrochloride
  • Vetibenzamin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Tripelennamine. Medical Subject Headings (MeSH). 2026. Unique ID D014309. http://id.nlm.nih.gov/mesh/2026/D014309
  2. Tripelennamine. In: Wikipedia. https://en.wikipedia.org/wiki/Tripelennamine
  3. Tripelennamine. In: Wikidata. https://www.wikidata.org/wiki/Q415203
  4. Tripelennamine. In: PubChem Compound. CID 5587. https://pubchem.ncbi.nlm.nih.gov/compound/5587