Chemicals and Drugs

Triprolidine

Histamine H1 antagonist used in allergic rhinitis; ASTHMA; and URTICARIA. It is a component of COUGH and COLD medicines. It may cause drowsiness.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Histamine H1 antagonist used in allergic rhinitis; ASTHMA; and URTICARIA. It is a component of COUGH and COLD medicines. It may cause drowsiness.

Chemical Identity

Chemical Information

Molecular Formula
C19H22N2
Molecular Weight
278.4 g/mol
CAS Registry No.
486-12-4
IUPAC Name
2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine
InChIKey
CBEQULMOCCWAQT-WOJGMQOQSA-N
SMILES
CC1=CC=C(C=C1)/C(=C\CN2CCCC2)/C3=CC=CC=N3
MeSH Unique ID
D014311
Source
PubChem CID 5282443

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Actidil
  • Pro Actidil
  • Triprolidine Hydrochloride
  • Triprolidine Hydrochloride Anhydrous
  • Triprolidine Monohydrochloride
  • Triprolidine Monohydrochloride, (Z)-Isomer
  • Triprolidine Monohydrochloride, Monohydrate
  • Triprolidine Oxalate
  • Triprolidine Oxalate, (trans)-Isomer
  • Triprolidine, (Z)-Isomer
  • Anhydrous, Triprolidine Hydrochloride
  • Hydrochloride Anhydrous, Triprolidine
  • Hydrochloride, Triprolidine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(66); was see under PYRIDINES 1966-90

MeSH Hierarchy

Tree Number

  1. D03w.383.725w.932w

AMA Style

References

  1. National Library of Medicine. Triprolidine. Medical Subject Headings (MeSH). 2026. Unique ID D014311. http://id.nlm.nih.gov/mesh/2026/D014311
  2. Triprolidine. In: Wikipedia. https://en.wikipedia.org/wiki/Triprolidine
  3. Triprolidine. In: Wikidata. https://www.wikidata.org/wiki/Q417654
  4. Triprolidine. In: PubChem Compound. CID 5282443. https://pubchem.ncbi.nlm.nih.gov/compound/5282443