Structured Summary
Abstract
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.
MeSH Record
Classification
Broader headings
Narrower headings
- 4-1BB Ligand
- B-Cell Activating Factor
- beta2 Heterotrimer Lymphotoxin alpha1
- CD27 Ligand
- CD30 Ligand
- CD40 Ligand
- Cytokine TWEAK
- Ectodysplasins
- Fas Ligand Protein
- Lymphotoxin-alpha
- Lymphotoxin-beta
- OX40 Ligand
- RANK Ligand
- TNF-Related Apoptosis-Inducing Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 13
- Tumor Necrosis Factor Ligand Superfamily Member 14
- Tumor Necrosis Factor Ligand Superfamily Member 15
- Tumor Necrosis Factor-alpha
Related Concepts
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MeSH Record
Synonyms
4 entry terms
- TNF Receptor Ligands
- Necrosis Factors, Tumor
- Receptor Ligands, TNF
- Tumor Necrosis Factor Superfamily Ligands
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2005
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Tumor Necrosis Factors. Medical Subject Headings (MeSH). 2026. Unique ID D048069. http://id.nlm.nih.gov/mesh/2026/D048069
- Tumor Necrosis Factors. In: Wikipedia. https://en.wikipedia.org/wiki/Tumor_necrosis_factor_superfamily
- Tumor Necrosis Factors. In: Wikidata. https://www.wikidata.org/wiki/Q424381