Chemicals and Drugs

Type C Phosphofructokinase-1

An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits.

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Synonyms

4 entry terms
  • 6-Phosphofructokinase, Platelet Type
  • Phosphofructo-1-kinase Isozyme C
  • Phosphofructokinase-1, Type C
  • Phosphofructokinase 1, Type C

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002

MeSH Record

Previous Indexing

  • 6-Phosphofructokinase (1977-2001)

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References

  1. National Library of Medicine. Type C Phosphofructokinase-1. Medical Subject Headings (MeSH). 2026. Unique ID D025502. http://id.nlm.nih.gov/mesh/2026/D025502
  2. Type C Phosphofructokinase-1. In: Wikipedia. https://en.wikipedia.org/wiki/PFKP
  3. Type C Phosphofructokinase-1. In: Wikidata. https://www.wikidata.org/wiki/Q21120435