Chemicals and Drugs

Uncoupling Protein 2

A mitochondrial uncoupling protein that is expressed in many tissues and exhibits the greatest expression in SKELETAL MUSCLE. It regulates mitochondrial ATP production and the generation of REACTIVE OXYGEN SPECIES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mitochondrial uncoupling protein that is expressed in many tissues and exhibits the greatest expression in SKELETAL MUSCLE. It regulates mitochondrial ATP production and the generation of REACTIVE OXYGEN SPECIES.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Mitochondrial Uncoupling Protein 2
  • SLC25A8 Protein
  • Solute Carrier Family 25 Member 8
  • UCP2 Protein
  • Uncoupling Protein-2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1997)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.937w.598w.750
  2. D12.776w.543w.585w.475w.688w.750
  3. D12.776w.543w.585w.937w.696w.750
  4. D12.776w.575.750w.688w.750

AMA Style

References

  1. National Library of Medicine. Uncoupling Protein 2. Medical Subject Headings (MeSH). 2026. Unique ID D000071246. http://id.nlm.nih.gov/mesh/2026/D000071246
  2. Uncoupling Protein 2. In: Wikidata. https://www.wikidata.org/wiki/Q21120688