Structured Summary
Abstract
Mitochondrial anion carrier proteins that function as dimers and form proton channels in the INNER MITOCHONDRIAL MEMBRANE which creates proton leaks and uncouples OXIDATIVE PHOSPHORYLATION from ATP synthesis, resulting in the generation of heat instead of ATP.
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Synonyms
6 entry terms
- Mitochondrial UCPs
- Uncoupling Protein
- Uncoupling Proteins
- Protein, Uncoupling
- UCPs, Mitochondrial
- Uncoupling Proteins, Mitochondrial
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Membrane Proteins (1998-2016)
- Mitochondrial Proteins (1998-2016)
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References
- National Library of Medicine. Mitochondrial Uncoupling Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D000071245. http://id.nlm.nih.gov/mesh/2026/D000071245
- Mitochondrial Uncoupling Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Uncoupling_protein
- Mitochondrial Uncoupling Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24720289