Chemicals and Drugs

Uncoupling Protein 3

A mitochondrial uncoupling protein that is expressed in heart and skeletal muscle tissues. It functions to regulate tissue respiration, energy balance, and THERMOGENESIS. Mutations in the UCP3 gene are associated with OBESITY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mitochondrial uncoupling protein that is expressed in heart and skeletal muscle tissues. It functions to regulate tissue respiration, energy balance, and THERMOGENESIS. Mutations in the UCP3 gene are associated with OBESITY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Mitochondrial Uncoupling Protein 3
  • SLC25A9 Protein
  • Solute Carrier Family 25 Member 9
  • UCP3 Protein
  • Uncoupling Protein-3

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1997)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.937w.598w.875
  2. D12.776w.543w.585w.475w.688w.875
  3. D12.776w.543w.585w.937w.696w.875
  4. D12.776w.575.750w.688w.875

AMA Style

References

  1. National Library of Medicine. Uncoupling Protein 3. Medical Subject Headings (MeSH). 2026. Unique ID D000071247. http://id.nlm.nih.gov/mesh/2026/D000071247
  2. Uncoupling Protein 3. In: Wikidata. https://www.wikidata.org/wiki/Q21121747