Chemicals and Drugs

Venturicidins

Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function.

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Classification

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Drug Class

Pharmacological Action

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Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

uncoupling agents & antifungal antibiotics; from Streptomyces

MeSH Record

History Note

91(77); was see under LACTONES 1977-90

MeSH Record

Previous Indexing

  • Antibiotics, Antifungal (1973-1976)
  • Glycosides (1973-1974)
  • Lactones (1973-1976)
  • Rhamnose (1973-1974)

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References

  1. National Library of Medicine. Venturicidins. Medical Subject Headings (MeSH). 2026. Unique ID D014698. http://id.nlm.nih.gov/mesh/2026/D014698
  2. Venturicidins. In: Wikipedia. https://en.wikipedia.org/wiki/Venturicidin
  3. Venturicidins. In: Wikidata. https://www.wikidata.org/wiki/Q7920447