Structured Summary
Abstract
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
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Classification
Broader headings
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Synonyms
9 entry terms
- Wingless Type Protein
- Wingless Type Proteins
- Wnt Factor
- Wnt Factors
- Wnt Protein
- Factor, Wnt
- Protein, Wingless Type
- Protein, Wnt
- Type Protein, Wingless
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1987)
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AMA Style
References
- National Library of Medicine. Wnt Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D051153. http://id.nlm.nih.gov/mesh/2026/D051153
- Wnt Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Wnt_protein
- Wnt Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q77938923