Structured Summary
Abstract
The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.
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Synonyms
15 entry terms
- Genes, bcl-2
- Gene, bcl-2
- Genes, bcl 2
- bcl 2 Genes
- bcl-2 Gene
- c-bcl-2 Genes
- c-bcl-2 Proto-Oncogenes
- Gene, c-bcl-2
- Genes, c-bcl-2
- Proto-Oncogene, c-bcl-2
- Proto-Oncogenes, c-bcl-2
- c bcl 2 Genes
- c bcl 2 Proto Oncogenes
- c-bcl-2 Gene
- c-bcl-2 Proto-Oncogene
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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Indexing Annotation
bcl stands for "B-Cell Leukemia"
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History Note
97
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Previous Indexing
- Oncogenes (1984-1996)
- Proto-Oncogenes (1988-1996)
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References
- National Library of Medicine. bcl-2 Genes. Medical Subject Headings (MeSH). 2026. Unique ID D019254. http://id.nlm.nih.gov/mesh/2026/D019254
- bcl-2 Genes. In: Wikidata. https://www.wikidata.org/wiki/Q14863436