Structured Summary
Abstract
Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.
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Synonyms
6 entry terms
- 3'-orf Protein
- Gene Product, nef
- Gene Products, nef
- nef Protein
- 3' orf Protein
- nef Gene Product
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
91(90); was see under VIRAL REGULATORY PROTEINS 1990
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Previous Indexing
- Retroviridae Proteins (1987-1989)
- Viral Proteins (1987-1988)
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AMA Style
References
- National Library of Medicine. nef Gene Products. Medical Subject Headings (MeSH). 2026. Unique ID D015693. http://id.nlm.nih.gov/mesh/2026/D015693
- nef Gene Products. In: Wikipedia. https://en.wikipedia.org/wiki/Nef_(protein)
- nef Gene Products. In: Wikidata. https://www.wikidata.org/wiki/Q77948205