Chemicals and Drugs

p300-CBP-Associated Factor

A p300-CBP transcription factor with intrinsic HISTONE ACETYLASE activity that functions to promote TRANSCRIPTIONAL ACTIVATION. Among its functions is suppression of the CELL CYCLE where it competes with ADENOVIRUS E1A PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A p300-CBP transcription factor with intrinsic HISTONE ACETYLASE activity that functions to promote TRANSCRIPTIONAL ACTIVATION. Among its functions is suppression of the CELL CYCLE where it competes with ADENOVIRUS E1A PROTEINS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Histone Acetylase p300
  • PCAF Acetylase
  • PCAF Histone Acetylase
  • p300 Acetyltransferase
  • p300-CREB-Binding Protein-Associated Factor

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1996)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.050w.134w.415w.500w.575.601
  2. D12.776w.930w.680.601

AMA Style

References

  1. National Library of Medicine. p300-CBP-Associated Factor. Medical Subject Headings (MeSH). 2026. Unique ID D000099224. http://id.nlm.nih.gov/mesh/2026/D000099224
  2. p300-CBP-Associated Factor. In: Wikidata. https://www.wikidata.org/wiki/Q7118491