Structured Summary
Abstract
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
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Synonyms
7 entry terms
- p300-CBP Coactivator
- p300-CBP Protein
- Coactivator, p300-CBP
- Transcription Factors, p300-CBP
- p300 CBP Coactivator
- p300 CBP Protein
- p300 CBP Transcription Factors
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1994)
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References
- National Library of Medicine. p300-CBP Transcription Factors. Medical Subject Headings (MeSH). 2026. Unique ID D050880. http://id.nlm.nih.gov/mesh/2026/D050880
- p300-CBP Transcription Factors. In: Wikidata. https://www.wikidata.org/wiki/Q78195832