Structured Summary
Abstract
Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
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Synonyms
27 entry terms
- Genes, rel
- Gene, rel
- rel Gene
- c-rel Genes
- c-rel Proto-Oncogenes
- rel Oncogene
- v-rel Genes
- v-rel Oncogenes
- Gene, c-rel
- Gene, v-rel
- Genes, c-rel
- Genes, v-rel
- Oncogene, rel
- Oncogene, v-rel
- Oncogenes, rel
- Oncogenes, v-rel
- Proto-Oncogene, c-rel
- Proto-Oncogenes, c-rel
- c rel Genes
- c rel Proto Oncogenes
- c-rel Gene
- c-rel Proto-Oncogene
- rel Oncogenes
- v rel Genes
- v rel Oncogenes
- v-rel Gene
- v-rel Oncogene
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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History Note
2000; use ONCOGENES 1988-1999
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Previous Indexing
- Genes, Viral (1983-1999)
- Oncogenes (1983-1999)
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References
- National Library of Medicine. rel Genes. Medical Subject Headings (MeSH). 2026. Unique ID D020573. http://id.nlm.nih.gov/mesh/2026/D020573
- rel Genes. In: Wikidata. https://www.wikidata.org/wiki/Q70578120