Chemicals and Drugs

trkB Receptor

A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.

MeSH Record

Classification

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MeSH Record

Synonyms

10 entry terms
  • BDNF Receptor
  • Brain Derived Neurotrophic Factor Receptor
  • NTRK2 Receptor
  • Neurotrophic Factor, Brain-Derived, Receptor
  • Neurotrophic Tyrosine Kinase Receptor Type 2
  • Receptor, Neurotrophic Tyrosine Kinase Type 2
  • Receptor, trkB
  • trkB(gp145) Protein
  • Receptor, BDNF
  • Receptor, NTRK2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000; for TRKB(GP145) PROTEIN use RECEPTOR, TYPE 2 NEUROTROPHIC TYROSINE KINASE (NM) 1990-1999; for BDNF RECEPTOR use RECEPTOR, TYPE 2 NEUROTROPHIC TYROSINE KINASE (NM) 1995-1999

MeSH Record

Previous Indexing

  • Membrane Glycoproteins (1990-1993)
  • Protein-Tyrosine Kinase (1990-1993)
  • Receptor Protein-Tyrosine Kinase (1994-1999)
  • Receptors, Growth Factor (1990-1993)
  • Receptors, Nerve Growth Factor (1994-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. trkB Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D020813. http://id.nlm.nih.gov/mesh/2026/D020813
  2. trkB Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q24766693