Structured Summary
Abstract
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
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Broader headings
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MeSH Record
Synonyms
35 entry terms
- Alzheimer Dementia
- Alzheimer Sclerosis
- Alzheimer Syndrome
- Alzheimer Type Senile Dementia
- Alzheimer's Disease
- Alzheimer's Diseases
- Alzheimer-Type Dementia (ATD)
- Dementia, Alzheimer Type
- Dementia, Primary Senile Degenerative
- Dementia, Senile
- Primary Senile Degenerative Dementia
- Senile Dementia, Alzheimer Type
- Alzheimer Dementias
- Alzheimer Diseases
- Alzheimer Type Dementia
- Alzheimer Type Dementia (ATD)
- Alzheimers Diseases
- Dementia, Alzheimer
- Dementia, Alzheimer-Type (ATD)
- Sclerosis, Alzheimer
- Senile Dementia
- Acute Confusional Senile Dementia
- Alzheimer Disease, Early Onset
- Alzheimer Disease, Late Onset
- Alzheimer's Disease, Focal Onset
- Dementia, Presenile
- Early Onset Alzheimer Disease
- Familial Alzheimer Disease (FAD)
- Focal Onset Alzheimer's Disease
- Late Onset Alzheimer Disease
- Presenile Alzheimer Dementia
- Senile Dementia, Acute Confusional
- Alzheimer Disease, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
- Presenile Dementia
MeSH Record
Aspects Covered
35 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
History Note
1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999
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AMA Style
References
- National Library of Medicine. Alzheimer Disease. Medical Subject Headings (MeSH). 2026. Unique ID D000544. http://id.nlm.nih.gov/mesh/2026/D000544
- Alzheimer Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Alzheimer%27s_disease
- Alzheimer Disease. In: Wikidata. https://www.wikidata.org/wiki/Q11081