Chemicals and Drugs

CARD Signaling Adaptor Proteins

A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.

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Synonyms

1 entry terms
  • Caspase Activation and Recruitment Domain Signaling Proteins

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.024w.131
  2. D12.644w.360.075.358
  3. D12.776w.157w.057w.006
  4. D12.776w.476.024w.139
  5. D12.776w.476.075.358

AMA Style

References

  1. National Library of Medicine. CARD Signaling Adaptor Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D053468. http://id.nlm.nih.gov/mesh/2026/D053468
  2. CARD Signaling Adaptor Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q77040095