Chemicals and Drugs

Class I Phosphatidylinositol 3-Kinases

A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Class I Phosphatidylinositol 3-Kinase
  • Phosphatidylinositol 3-Kinase, Class I
  • Class I Phosphatidylinositol 3 Kinase
  • Class I Phosphatidylinositol 3 Kinases
  • Phosphatidylinositol 3 Kinase, Class I

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

MeSH Record

Previous Indexing

  • Phosphatidylinositol 3-Kinases (1998-2010)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Class I Phosphatidylinositol 3-Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D058534. http://id.nlm.nih.gov/mesh/2026/D058534
  2. Class I Phosphatidylinositol 3-Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Class_I_PI_3-kinases
  3. Class I Phosphatidylinositol 3-Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q5127991