Structured Summary
Abstract
Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.
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Classification
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
13 entry terms
- C3b Inactivators
- C3b Inhibitors
- Complement 3b Inactivators
- Complement 3b Inhibitors
- Complement C3b Inactivators
- Complement C3b Inhibitor Proteins
- Conglutinogen Activating Factors
- Factors, Conglutinogen Activating
- Inactivators, C3b
- Inactivators, Complement 3b
- Inactivators, Complement C3b
- Inhibitors, C3b
- Inhibitors, Complement 3b
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1978)
MeSH Record
Previous Indexing
- Complement 3 (1975-1977)
- Serum Globulins (1970-1977)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Complement C3b Inactivator Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D003180. http://id.nlm.nih.gov/mesh/2026/D003180
- Complement C3b Inactivator Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q78345957