Chemicals and Drugs

Digitoxin

A cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)

Chemical Identity

Chemical Information

Molecular Formula
C41H64O13
Molecular Weight
764.9 g/mol
CAS Registry No.
71-63-6
IUPAC Name
3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
InChIKey
WDJUZGPOPHTGOT-XUDUSOBPSA-N
SMILES
C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5CC[C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)C)C)C)O)O
MeSH Unique ID
D004074
Source
PubChem CID 441207

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Coramedan
  • Digimed
  • Digimerck
  • Digitaline Nativelle
  • Digitoxin AWD
  • Digitoxin Bürger
  • Digitoxin Didier
  • Digitoxin-Philo
  • Digophton
  • AWD, Digitoxin
  • Bürger, Digitoxin
  • Didier, Digitoxin
  • Digitoxin Philo
  • Nativelle, Digitaline

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a Digitalis glycoside; do not confuse with DIGOXIN

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.155.580w.130.500.336w
  2. D04w.210.500w.155.580w.130.625w
  3. D09w.408w.180w.261.336w

AMA Style

References

  1. National Library of Medicine. Digitoxin. Medical Subject Headings (MeSH). 2026. Unique ID D004074. http://id.nlm.nih.gov/mesh/2026/D004074
  2. Digitoxin. In: Wikipedia. https://en.wikipedia.org/wiki/Digitoxin
  3. Digitoxin. In: Wikidata. https://www.wikidata.org/wiki/Q423890
  4. Digitoxin. In: PubChem Compound. CID 441207. https://pubchem.ncbi.nlm.nih.gov/compound/441207