Chemicals and Drugs

Cardenolides

C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

1 entry terms
  • Cardenolide

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

includes cardadienolides & cardatrienolides; do not confuse with CARDANOLIDES

MeSH Record

History Note

77

MeSH Record

Previous Indexing

  • Cardanolides (1968-1976)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.155.580w.130

AMA Style

References

  1. National Library of Medicine. Cardenolides. Medical Subject Headings (MeSH). 2026. Unique ID D002298. http://id.nlm.nih.gov/mesh/2026/D002298
  2. Cardenolides. In: Wikidata. https://www.wikidata.org/wiki/Q50377146