Chemicals and Drugs

Fluocortolone

A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.

Chemical Identity

Chemical Information

Molecular Formula
C22H29FO4
Molecular Weight
376.5 g/mol
CAS Registry No.
152-97-6
IUPAC Name
(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
InChIKey
GAKMQHDJQHZUTJ-ULHLPKEOSA-N
SMILES
C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)CO)C)O)C)F
MeSH Unique ID
D005448
Source
PubChem CID 9053

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Fluocortolone Caproate
  • Fluocortolone Pivalate
  • Ultralan
  • Caproate, Fluocortolone
  • Pivalate, Fluocortolone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

80(75); was see under PREGNADIENEDIOLS 1975-79; FLUORMETHYLDEHYDROCORTICOSTERONE was see FLUOCORTOLONE 1975-94

MeSH Record

Previous Indexing

  • Ketosteroids (1974)
  • Pregnadienediols (1974)
  • Steroids, Fluorinated (1974)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.719.320w
  2. D04w.210.500w.908.405w

MeSH Record

NLM Classification

QV 60

AMA Style

References

  1. National Library of Medicine. Fluocortolone. Medical Subject Headings (MeSH). 2026. Unique ID D005448. http://id.nlm.nih.gov/mesh/2026/D005448
  2. Fluocortolone. In: Wikipedia. https://en.wikipedia.org/wiki/Fluocortolone
  3. Fluocortolone. In: Wikidata. https://www.wikidata.org/wiki/Q5462793
  4. Fluocortolone. In: PubChem Compound. CID 9053. https://pubchem.ncbi.nlm.nih.gov/compound/9053