Chemicals and Drugs

GTP-Binding Proteins

Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

17 entry terms
  • G-Protein
  • G-Proteins
  • GTP-Binding Protein
  • GTP-Regulatory Protein
  • GTP-Regulatory Proteins
  • Guanine Nucleotide Coupling Protein
  • Guanine Nucleotide Regulatory Proteins
  • G Protein
  • G Proteins
  • GTP Binding Protein
  • GTP Binding Proteins
  • GTP Regulatory Protein
  • GTP Regulatory Proteins
  • Protein, GTP-Binding
  • Protein, GTP-Regulatory
  • Proteins, GTP-Binding
  • Proteins, GTP-Regulatory

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics; GTP stands for Guanosine TriPhosphate

MeSH Record

History Note

1997(1985)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 55.2

AMA Style

References

  1. National Library of Medicine. GTP-Binding Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D019204. http://id.nlm.nih.gov/mesh/2026/D019204
  2. GTP-Binding Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q76718498