Chemicals and Drugs

Gi-Go GTP-Binding Protein alpha Subunits

A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by their ability to inhibit ADENYLYL CYCLASES. Members of this family can couple to beta and gamma G-protein subunits that activate POTASSIUM CHANNELS. The Gi-Go part of the name is also spelled Gi/Go.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by their ability to inhibit ADENYLYL CYCLASES. Members of this family can couple to beta and gamma G-protein subunits that activate POTASSIUM CHANNELS. The Gi-Go part of the name is also spelled Gi/Go.

MeSH Record

Classification

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MeSH Record

Synonyms

61 entry terms
  • G-Protein, Gi-Go Subunits
  • G-Protein, Gi-Go alpha Family
  • GTP-Binding Protein alpha Subunits, Gi-Go
  • Gi-Go G-Proteins
  • G Protein, Gi Go Subunits
  • G Protein, Gi Go alpha Family
  • G-Proteins, Gi-Go
  • GTP Binding Protein alpha Subunits, Gi Go
  • Gi Go G Proteins
  • Gi-Go Subunits G-Protein
  • Subunits G-Protein, Gi-Go
  • G Protein Go
  • G Protein Subunit alphaoA
  • G Protein Subunit alphaoC
  • G(o) Protein
  • G(o1)alpha
  • G-Protein, Gi Subunit
  • G-Protein, Go Subunit
  • G-Protein, Go1 Subunit
  • G-Protein, Inhibitory Gi
  • G-Protein, Inhibitory Go
  • GTP-Binding Protein alpha Subunit, Gi
  • GTP-Binding Protein alpha Subunit, Go
  • GTP-Binding Protein alpha Subunit, Go1
  • GTP-Binding Protein alpha Subunit, GoA
  • GTP-Binding Protein alpha Subunit, GoC
  • Gi alpha Subunit
  • Gi, Inhibitory G-Protein
  • Gi-Alpha Protein
  • Go Alpha Subunit
  • Guanine Nucleotide-Binding Protein Go
  • Ni Protein
  • Alpha Subunit, Go
  • G Protein, Gi Subunit
  • G Protein, Go Subunit
  • G Protein, Go1 Subunit
  • G Protein, Inhibitory Gi
  • G Protein, Inhibitory Go
  • GTP Binding Protein alpha Subunit, Gi
  • GTP Binding Protein alpha Subunit, Go
  • GTP Binding Protein alpha Subunit, Go1
  • GTP Binding Protein alpha Subunit, GoA
  • GTP Binding Protein alpha Subunit, GoC
  • Gi Alpha Protein
  • Gi G-Protein, Inhibitory
  • Gi Subunit G-Protein
  • Gi, Inhibitory G Protein
  • Go G-Protein, Inhibitory
  • Go Subunit G-Protein
  • Go, G Protein
  • Go1 Subunit G-Protein
  • Guanine Nucleotide Binding Protein Go
  • Inhibitory G-Protein Gi
  • Inhibitory Gi G-Protein
  • Inhibitory Go G-Protein
  • Subunit G-Protein, Gi
  • Subunit G-Protein, Go
  • Subunit G-Protein, Go1
  • Subunit, Gi alpha
  • Subunit, Go Alpha
  • alpha Subunit, Gi

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004(1997); for GUANINE NUCLEOTIDE-BINDING PROTEIN GO use GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO (NM) 1997-2003

MeSH Record

Previous Indexing

  • G-Proteins (1985-1996)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Gi-Go GTP-Binding Protein alpha Subunits. Medical Subject Headings (MeSH). 2026. Unique ID D019206. http://id.nlm.nih.gov/mesh/2026/D019206
  2. Gi-Go GTP-Binding Protein alpha Subunits. In: Wikipedia. https://en.wikipedia.org/wiki/Gi_alpha_subunit
  3. Gi-Go GTP-Binding Protein alpha Subunits. In: Wikidata. https://www.wikidata.org/wiki/Q24719569