Structured Summary
Abstract
A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.
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Synonyms
18 entry terms
- Ig Switch Region
- Ig Switch Sequences
- Switch Region, Immunoglobulin
- Ig Switch Regions
- Ig Switch Sequence
- Immunoglobulin Switch Regions
- Region, Ig Switch
- Region, Immunoglobulin Switch
- Regions, Ig Switch
- Regions, Immunoglobulin Switch
- Sequence, Ig Switch
- Sequences, Ig Switch
- Switch Region, Ig
- Switch Regions, Ig
- Switch Regions, Immunoglobulin
- Switch Sequence, Ig
- Switch Sequences, Ig
- Heavy-Chain Mu Switch Region
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Aspects Covered
7 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, isolation & purification, physiology, radiation effects.
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History Note
88
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Previous Indexing
- Genes, Structural (1977-1987)
- Immunoglobulin Constant Region (1979-1987)
- Immunoglobulin Variable Region (1977-1987)
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References
- National Library of Medicine. Immunoglobulin Switch Region. Medical Subject Headings (MeSH). 2026. Unique ID D007134. http://id.nlm.nih.gov/mesh/2026/D007134
- Immunoglobulin Switch Region. In: Wikidata. https://www.wikidata.org/wiki/Q71147371