Structured Summary
Abstract
Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.
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Classification
Broader headings
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Synonyms
14 entry terms
- CD49c-CD29
- Epiligrin Receptor
- Galactoprotein b3
- Gap b3
- Integrin alpha(3)beta(1)
- Laminin-5 Receptor (alpha3beta1 integrin)
- VLA-3
- alpha3beta1 Epiligrin Receptor
- alpha3beta1 Integrin
- Epiligrin Receptor, alpha3beta1
- Integrin, alpha3beta1
- Receptor, Epiligrin
- Receptor, alpha3beta1 Epiligrin
- alpha3beta1, Integrin
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2003; use INTEGRIN ALPHA3BETA1 (NM) 1992-2002
MeSH Record
Previous Indexing
- Integrins (1992-2002)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Integrin alpha3beta1. Medical Subject Headings (MeSH). 2026. Unique ID D039201. http://id.nlm.nih.gov/mesh/2026/D039201
- Integrin alpha3beta1. In: Wikidata. https://www.wikidata.org/wiki/Q50257504