Structured Summary
Abstract
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
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Synonyms
4 entry terms
- Deficiency Syndrome, Leukocyte-Adhesion
- Deficiency Syndrome, Leukocyte Adhesion
- Leukocyte Adhesion Deficiency Syndrome
- Leukocyte-Adhesion Deficiency Syndromes
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Aspects Covered
34 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
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History Note
95
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Previous Indexing
- Immunologic Deficiency Syndromes (1988-1994)
- Receptors, Leukocyte-Adhesion/deficiency (1988-1990)
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References
- National Library of Medicine. Leukocyte-Adhesion Deficiency Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D018370. http://id.nlm.nih.gov/mesh/2026/D018370
- Leukocyte-Adhesion Deficiency Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency
- Leukocyte-Adhesion Deficiency Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1154422