Chemicals and Drugs

CD18 Antigens

Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.

MeSH Record

Classification

Broader headings

Related Concepts

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See Also

MeSH Record

Synonyms

9 entry terms
  • Antigens, CD18
  • CD18 Antigen
  • Integrin beta2
  • beta2 Integrin
  • p150,95 beta-Subunit
  • Integrin, beta2
  • beta-Subunit, p150,95
  • beta2, Integrin
  • p150,95 beta Subunit

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018 (1986)

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1994)
  • Membrane Glycoproteins (1986-1989)
  • Membrane Proteins (1986-1987)
  • Receptors, Leukocyte-Adhesion (1989-1991)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.200w.275w.750w
  2. D12.776w.395w.550w.200w.275w.750w
  3. D12.776w.543w.550w.200w.275w.750w
  4. D12.776w.543w.750w.705w.408w.200.249w
  5. D12.776w.543w.750w.705w.408w.600.100w.750w
  6. D12.776w.543w.750w.705w.833.249w.750w
  7. D23.050w.301.264.894.118w
  8. D23.050w.301.350w.275w.750w
  9. D23.101w.100.894.118w

AMA Style

References

  1. National Library of Medicine. CD18 Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D018821. http://id.nlm.nih.gov/mesh/2026/D018821
  2. CD18 Antigens. In: Wikipedia. https://en.wikipedia.org/wiki/Integrin_beta_2
  3. CD18 Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q2458503