Structured Summary
Abstract
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
See Also
MeSH Record
Synonyms
27 entry terms
- Adhesive Receptor Mac-1
- CR3 Receptor
- Complement 3 Receptor
- Integrin alpha(M)beta(2)
- Integrin alpha-M beta-2
- Integrin alphaMbeta2
- Mac-1 Adhesive Receptor
- Mac-1 Antigen
- Mac-1 Receptor
- Mo1 Antigen Receptor
- Mo1 Glycoprotein Receptor
- Receptor, CR3
- Receptor, Complement 3
- Receptor, Mo1 Antigen
- Receptor, Mo1 Glycoprotein
- Adhesive Receptor, Mac-1
- Antigen Receptor, Mo1
- Antigen, Macrophage-1
- Glycoprotein Receptor, Mo1
- Integrin alpha M beta 2
- Mac 1 Adhesive Receptor
- Mac 1 Antigen
- Mac 1 Receptor
- Macrophage 1 Antigen
- Receptor, Mac-1 Adhesive
- alpha-M beta-2, Integrin
- alphaMbeta2, Integrin
MeSH Record
Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
91; INTEGRIN ALPHA(M)BETA(2) was NM 1994-95
MeSH Record
Previous Indexing
- Antigens, Differentiation (1988-1990)
- Receptors, Leukocyte-Adhesion (1989-1990)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Macrophage-1 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D016177. http://id.nlm.nih.gov/mesh/2026/D016177
- Macrophage-1 Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/Macrophage-1_antigen
- Macrophage-1 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q4043525