Chemicals and Drugs

Mitogen-Activated Protein Kinase 10

A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.

MeSH Record

Classification

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MeSH Record

Synonyms

17 entry terms
  • JNK3 Mitogen Activated Protein Kinase
  • MAP Kinase p49(3F12)
  • MAPK10 Mitogen-Activated Protein Kinase
  • Mitogen Activated Protein Kinase p49(3F12)
  • Stress-Activated Protein Kinase JNK3
  • c-jun Kinase 3
  • c-jun N-Terminal Kinase 3
  • p49 3F12 Kinase
  • p49(3F12) SAP Kinase
  • p54-SAPK(beta)
  • 3F12 Kinase, p49
  • Kinase 3, c-jun
  • MAPK10 Mitogen Activated Protein Kinase
  • Mitogen Activated Protein Kinase 10
  • Stress Activated Protein Kinase JNK3
  • c jun Kinase 3
  • c jun N Terminal Kinase 3

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005(1995)

MeSH Record

Previous Indexing

  • Mitogen-Activated Protein Kinases (2000-2004)
  • Protein-Serine-Threonine Kinases (1995-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Mitogen-Activated Protein Kinase 10. Medical Subject Headings (MeSH). 2026. Unique ID D048057. http://id.nlm.nih.gov/mesh/2026/D048057
  2. Mitogen-Activated Protein Kinase 10. In: Wikidata. https://www.wikidata.org/wiki/Q21139471