Chemicals and Drugs

Mitogen-Activated Protein Kinase 8

A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING.

MeSH Record

Classification

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MeSH Record

Synonyms

18 entry terms
  • JNK1 Kinase
  • MAPK8 Mitogen-Activated Protein Kinase
  • SAP Kinase-1
  • SAPK1 Mitogen-Activated Protein Kinase
  • Stress-Activated Protein Kinase 1
  • Stress-Activated Protein Kinase JNK1
  • Stress-Activated Protein Kinase gamma
  • c-jun Kinase-1
  • c-jun N-Terminal Kinase 1
  • MAPK8 Mitogen Activated Protein Kinase
  • Mitogen Activated Protein Kinase 8
  • SAP Kinase 1
  • SAPK1 Mitogen Activated Protein Kinase
  • Stress Activated Protein Kinase 1
  • Stress Activated Protein Kinase JNK1
  • Stress Activated Protein Kinase gamma
  • c jun Kinase 1
  • c jun N Terminal Kinase 1

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005(2000)

MeSH Record

Previous Indexing

  • Mitogen-Activated Protein Kinases (2000-2004)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Mitogen-Activated Protein Kinase 8. Medical Subject Headings (MeSH). 2026. Unique ID D048055. http://id.nlm.nih.gov/mesh/2026/D048055
  2. Mitogen-Activated Protein Kinase 8. In: Wikidata. https://www.wikidata.org/wiki/Q6714411