Chemicals and Drugs

Orphenadrine

A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

Chemical Identity

Chemical Information

Molecular Formula
C18H23NO
Molecular Weight
269.4 g/mol
CAS Registry No.
83-98-7
IUPAC Name
N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine
InChIKey
QVYRGXJJSLMXQH-UHFFFAOYSA-N
SMILES
CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C
MeSH Unique ID
D009966
Source
PubChem CID 4601

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Methyldiphenylhydramine
  • Disipal
  • Lysantin
  • Mefenamine
  • Mephenamine
  • Norflex
  • Norflex Orphenadrine Citrate
  • Orphenadrine Citrate
  • Orphenadrine Hydrochloride
  • Sodium Mefenamine
  • Citrate, Norflex Orphenadrine
  • Citrate, Orphenadrine
  • Hydrochloride, Orphenadrine
  • Mefenamine, Sodium
  • Orphenadrine Citrate, Norflex

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Orphenadrine. Medical Subject Headings (MeSH). 2026. Unique ID D009966. http://id.nlm.nih.gov/mesh/2026/D009966
  2. Orphenadrine. In: Wikipedia. https://en.wikipedia.org/wiki/Orphenadrine
  3. Orphenadrine. In: Wikidata. https://www.wikidata.org/wiki/Q3292273
  4. Orphenadrine. In: PubChem Compound. CID 4601. https://pubchem.ncbi.nlm.nih.gov/compound/4601