Chemicals and Drugs

PrP 27-30 Protein

Protease-resistant core of PrPSc, the abnormal isoform of PRION PROTEINS. PrP 27-30 is produced by limited proteolysis of the N-terminus of PrPSc.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Protease-resistant core of PrPSc, the abnormal isoform of PRION PROTEINS. PrP 27-30 is produced by limited proteolysis of the N-terminus of PrPSc.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

14 entry terms
  • Fibril-Protein, Scrapie-Associated
  • Fibrils, Scrapie-Associated
  • Scrapie Associated Fibril-Protein
  • Scrapie PrP 27-30 Protein
  • Scrapie-Associated Fibril-Protein
  • Scrapie-Associated Fibrils
  • Associated Fibril-Protein, Scrapie
  • Fibril Protein, Scrapie Associated
  • Fibril-Protein, Scrapie Associated
  • Fibrils, Scrapie Associated
  • PrP 27 30 Protein
  • Scrapie Associated Fibril Protein
  • Scrapie Associated Fibrils
  • Scrapie PrP 27 30 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pathogenicity, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

protease-resistant core of PRPSC proteins; PRP stands for Prion Protein; /pathogen permitted

MeSH Record

History Note

95; SCRAPIE-ASSOCIATED FIBRILS was see PRIONS 1992-94, was see SCRAPIE AGENT 1987-91; SCRAPIE PRP 27-30 PROTEIN was NM 1985-94; SCRAPIE ASSOCIATED FIBRIL-PROTEIN was NM 1984-94

MeSH Record

Previous Indexing

  • Prions (1992-1994)
  • Viral Proteins (1985-1991)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. PrP 27-30 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D018622. http://id.nlm.nih.gov/mesh/2026/D018622
  2. PrP 27-30 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q76721313