Structured Summary
Abstract
A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.
Chemical Identity
Chemical Information
- Molecular Formula
- C26H28ClNO
- Molecular Weight
- 406.0 g/mol
- CAS Registry No.
- 89778-26-7
- IUPAC Name
- 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
- InChIKey
- XFCLJVABOIYOMF-QPLCGJKRSA-N
- SMILES
- CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCl)\C2=CC=CC=C2)/C3=CC=CC=C3
- MeSH Unique ID
- D017312
- Source
- PubChem CID 3005573
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- FC-1157a
- Fareston
- Toremifene Citrate
- Toremifene Citrate (1:1)
- Toremifene, (E)-Isomer
- Citrate, Toremifene
- FC 1157a
- FC1157a
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
93; was TOREMIFENE (NM) 1985-92
MeSH Record
Previous Indexing
- Tamoxifen/analogs & derivatives (1985-1992)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Toremifene. Medical Subject Headings (MeSH). 2026. Unique ID D017312. http://id.nlm.nih.gov/mesh/2026/D017312
- Toremifene. In: Wikipedia. https://en.wikipedia.org/wiki/Toremifene
- Toremifene. In: Wikidata. https://www.wikidata.org/wiki/Q3993743
- Toremifene. In: PubChem Compound. CID 3005573. https://pubchem.ncbi.nlm.nih.gov/compound/3005573