Phenomena and Processes

Tumor Suppressor Genes

Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

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Synonyms

41 entry terms
  • Anti-Oncogenes
  • Antioncogenes
  • Cancer Suppressor Genes
  • Emerogenes
  • Genes, Cancer Suppressor
  • Genes, Onco-Suppressor
  • Genes, Tumor Suppressor
  • Oncogenes, Recessive
  • Tumor Suppressing Genes
  • Anti Oncogenes
  • Anti-Oncogene
  • Antioncogene
  • Cancer Suppressor Gene
  • Emerogene
  • Gene, Cancer Suppressor
  • Gene, Onco-Suppressor
  • Gene, Tumor Suppressing
  • Gene, Tumor Suppressor
  • Genes, Onco Suppressor
  • Genes, Tumor Suppressing
  • Onco-Suppressor Gene
  • Onco-Suppressor Genes
  • Oncogene, Recessive
  • Recessive Oncogene
  • Recessive Oncogenes
  • Suppressor Gene, Cancer
  • Suppressor Genes, Cancer
  • Tumor Suppressing Gene
  • Tumor Suppressor Gene
  • Genes, Growth Suppressor
  • Genes, Metastasis Suppressor
  • Growth Suppressor Genes
  • Metastasis Suppressor Genes
  • Gene, Growth Suppressor
  • Gene, Metastasis Suppressor
  • Growth Suppressor Gene
  • Metastasis Suppressor Gene
  • Suppressor Gene, Growth
  • Suppressor Gene, Metastasis
  • Suppressor Genes, Growth
  • Suppressor Genes, Metastasis

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Aspects Covered

4 allowable subheadings

Indexed with the subheadings drug effects, ethics, physiology, radiation effects.

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Indexing Annotation

Manual 24.4.4.3

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History Note

2002 (1991)

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Previous Indexing

  • Suppression, Genetic (1986-1990)

MeSH Hierarchy

Tree Numbers

  1. G05.360w.340w.024.340w.375.249w
  2. G05.360w.340w.024.340w.415.400w

MeSH Record

NLM Classification

QZ 210

AMA Style

References

  1. National Library of Medicine. Tumor Suppressor Genes. Medical Subject Headings (MeSH). 2026. Unique ID D016147. http://id.nlm.nih.gov/mesh/2026/D016147
  2. Tumor Suppressor Genes. In: Wikipedia. https://en.wikipedia.org/wiki/Tumor_suppressor_gene
  3. Tumor Suppressor Genes. In: Wikidata. https://www.wikidata.org/wiki/Q422445