Phenomena and Processes

p16 Genes

Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.

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Synonyms

17 entry terms
  • CDKN2 Genes
  • Genes, CDKN2
  • Genes, CDKN2A
  • Genes, MTS1
  • Genes, p16
  • Genes, p16INK4
  • Genes, p16INK4A
  • MTS1 Genes
  • p16INK4 Genes
  • CDKN2 Gene
  • CDKN2A Gene
  • CDKN2A Genes
  • MTS1 Gene
  • p16 Gene
  • p16INK4 Gene
  • p16INK4A Gene
  • p16INK4A Genes

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4 allowable subheadings

Indexed with the subheadings drug effects, ethics, physiology, radiation effects.

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History Note

98

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Previous Indexing

  • Genes, Suppressor, Tumor (1994-1997)

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Tree Numbers

  1. G05.360w.340w.024.340w.375.249w.375w
  2. G05.360w.340w.024.340w.415.400w.375w

AMA Style

References

  1. National Library of Medicine. p16 Genes. Medical Subject Headings (MeSH). 2026. Unique ID D019942. http://id.nlm.nih.gov/mesh/2026/D019942
  2. p16 Genes. In: Wikipedia. https://en.wikipedia.org/wiki/CDKN2A
  3. p16 Genes. In: Wikidata. https://www.wikidata.org/wiki/Q5009957