Structured Summary
Abstract
A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
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Classification
Broader headings
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MeSH Record
Synonyms
9 entry terms
- Ubiquitin-Activating Enzyme
- Ubiquitin-Activating Enzyme E1
- Ubiquitination Activating Enzyme E1
- Enzyme E1, Ubiquitin-Activating
- Enzyme, Ubiquitin-Activating
- Enzymes, Ubiquitin-Activating
- Ubiquitin Activating Enzyme
- Ubiquitin Activating Enzyme E1
- Ubiquitin Activating Enzymes
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2004; use UBIQUITIN-ACTIVATING ENZYMES (NM) 1983-2003
MeSH Record
Previous Indexing
- Ligases (1983-2003)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Ubiquitin-Activating Enzymes. Medical Subject Headings (MeSH). 2026. Unique ID D044764. http://id.nlm.nih.gov/mesh/2026/D044764
- Ubiquitin-Activating Enzymes. In: Wikidata. https://www.wikidata.org/wiki/Q41797132