Chemicals and Drugs

Ubiquitin-Conjugating Enzymes

A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES.

MeSH Record

Classification

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MeSH Record

Synonyms

10 entry terms
  • Ubiquitin-Conjugating Enzyme
  • Ubiquitin-Conjugating Enzyme E2
  • E2, Ubiquitin-Conjugating Enzyme
  • Enzyme E2, Ubiquitin-Conjugating
  • Enzyme, Ubiquitin-Conjugating
  • Enzymes, Ubiquitin-Conjugating
  • Ubiquitin Conjugating Enzyme
  • Ubiquitin Conjugating Enzyme E2
  • Ubiquitin Conjugating Enzymes
  • HHR6 Protein

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use UBIQUITIN-CONJUGATING ENZYMES (NM) 1990-2003

MeSH Record

Previous Indexing

  • Ligases (1989-2003)
  • Ubiquitins (1986-1988)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Ubiquitin-Conjugating Enzymes. Medical Subject Headings (MeSH). 2026. Unique ID D044763. http://id.nlm.nih.gov/mesh/2026/D044763
  2. Ubiquitin-Conjugating Enzymes. In: Wikidata. https://www.wikidata.org/wiki/Q70565343