Chemicals and Drugs

Antigen T-Cell Receptors

Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.

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Synonyms

16 entry terms
  • Antigen Receptors, T-Cell
  • Receptors, Antigen, T-Cell
  • Receptors, T-Cell Antigen
  • T-Cell Antigen Receptor
  • T-Cell Receptor
  • T-Cell Receptors
  • Antigen Receptor, T-Cell
  • Antigen Receptors, T Cell
  • Receptor, T-Cell
  • Receptor, T-Cell Antigen
  • Receptors, T Cell Antigen
  • Receptors, T-Cell
  • T Cell Antigen Receptor
  • T Cell Receptor
  • T Cell Receptors
  • T-Cell Antigen Receptors

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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Indexing Annotation

general or unspecified; prefer specifics; do not confuse their gamma-delta chains with gamma and delta chains which are subunits of CD3 antigens (index under ANTIGENS, CD3)

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History Note

80

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Previous Indexing

  • Lymphocytes (1966-1979)
  • T Lymphocytes (1973-1979)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.750w.705w.816.824w

MeSH Record

NLM Classification

QW 574

AMA Style

References

  1. National Library of Medicine. Antigen T-Cell Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D011948. http://id.nlm.nih.gov/mesh/2026/D011948
  2. Antigen T-Cell Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/T-cell_receptor
  3. Antigen T-Cell Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q412037