Chemicals and Drugs

Baculoviral IAP Repeat-Containing 3 Protein

A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Apoptosis Inhibitor 2
  • BIRC3 Protein
  • Baculoviral IAP Repeat Containing Protein 3
  • Cellular Inhibitor of Apoptosis-2
  • Hiap-1 Protein
  • IAP1 Protein
  • Inhibitor of Apoptosis 1 Protein
  • Inhibitor of Apoptosis Protein 1
  • c-IAP2 Protein
  • cIAP2 Protein
  • Apoptosis-2 Cellular Inhibitor
  • Baculoviral IAP Repeat Containing 3 Protein
  • Cellular Inhibitor of Apoptosis 2
  • Hiap 1 Protein
  • Inhibitor 2, Apoptosis

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018; for INHIBITOR OF APOPTOSIS 1 PROTEIN use INHIBITOR OF OF APOPTOSIS PROTEINS 2006-2017

MeSH Record

Previous Indexing

  • Inhibitor of Apoptosis Proteins (2006-2017)
  • Ubiquitin-Protein Ligases (2006-2017)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.464w.938.750.210w.250
  2. D12.644w.360.075.437w.250
  3. D12.776w.476.075.437w.250

AMA Style

References

  1. National Library of Medicine. Baculoviral IAP Repeat-Containing 3 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000075747. http://id.nlm.nih.gov/mesh/2026/D000075747
  2. Baculoviral IAP Repeat-Containing 3 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21101064