Chemicals and Drugs

Digoxigenin

3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide. A cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide. A cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.

Chemical Identity

Chemical Information

Molecular Formula
C23H34O5
Molecular Weight
390.5 g/mol
CAS Registry No.
1672-46-4
IUPAC Name
3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
InChIKey
SHIBSTMRCDJXLN-KCZCNTNESA-N
SMILES
C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2C[C@H]([C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O)O
MeSH Unique ID
D004076
Source
PubChem CID 15478

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

1 entry terms
  • Lanadigenin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a Digitalis glycoside; do not confuse with DIGITOXIGENIN; /biosyn permitted if by plant

MeSH Record

History Note

91(77); was see under DIGOXIN 1977-90

MeSH Record

Previous Indexing

  • Cardanolides (1968-1974)
  • Digoxin/AA (1975-1976)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.155.580w.130.688w.350w

AMA Style

References

  1. National Library of Medicine. Digoxigenin. Medical Subject Headings (MeSH). 2026. Unique ID D004076. http://id.nlm.nih.gov/mesh/2026/D004076
  2. Digoxigenin. In: Wikipedia. https://en.wikipedia.org/wiki/Digoxigenin
  3. Digoxigenin. In: Wikidata. https://www.wikidata.org/wiki/Q420728
  4. Digoxigenin. In: PubChem Compound. CID 15478. https://pubchem.ncbi.nlm.nih.gov/compound/15478