Chemicals and Drugs

Etanercept

A recombinant version of soluble human TNF receptor fused to an IgG FC fragment that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A recombinant version of soluble human TNF receptor fused to an IgG FC fragment that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Enbrel
  • Erelzi
  • Etanercept-szzs
  • Recombinant Human Dimeric TNF Receptor Type II-IgG Fusion Protein
  • TNF Receptor Type II-IgG Fusion Protein
  • TNFR-Fc Fusion Protein
  • TNR 001
  • TNR-001
  • TNT Receptor Fusion Protein
  • TNTR-Fc
  • Fusion Protein, TNFR-Fc
  • Recombinant Human Dimeric TNF Receptor Type II IgG Fusion Protein
  • TNF Receptor Type II IgG Fusion Protein
  • TNFR Fc Fusion Protein
  • TNR001

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Etanercept. Medical Subject Headings (MeSH). 2026. Unique ID D000068800. http://id.nlm.nih.gov/mesh/2026/D000068800
  2. Etanercept. In: Wikipedia. https://en.wikipedia.org/wiki/Etanercept
  3. Etanercept. In: Wikidata. https://www.wikidata.org/wiki/Q415343