Chemicals and Drugs

Fanconi Anemia Complementation Group L Protein

An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • FANCL Protein
  • Fanconi Anemia Group L Complementing Protein
  • Fanconi Anemia Group L Protein
  • PHD Finger Protein 9
  • Ubiquitin Ligase Protein PHF9

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (2003)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.464w.938.750.186
  2. D12.776w.313.937

AMA Style

References

  1. National Library of Medicine. Fanconi Anemia Complementation Group L Protein. Medical Subject Headings (MeSH). 2026. Unique ID D052240. http://id.nlm.nih.gov/mesh/2026/D052240
  2. Fanconi Anemia Complementation Group L Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21115069