Chemicals and Drugs

Glucuronosyltransferase

A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

35 entry terms
  • Glucuronic Transferase
  • Glucuronyltransferase
  • UDP Glucuronosyltransferase
  • UDP Glucuronyl Transferase
  • Glucuronosyltransferase, UDP
  • Glucuronyl Transferase, UDP
  • Transferase, Glucuronic
  • Transferase, UDP Glucuronyl
  • 17 beta-Hydroxysteroid UDP-Glucuronosyltransferase
  • 4-Nitrophenol-UDP-Glucuronosyltransferase
  • 7-Hydroxycoumarin UDP Glucuronyltransferase
  • Androsterone UDP-Glucuronosyltransferase
  • Bilirubin UDP-Glucuronyltransferase
  • Estrogen UDP-Glucuronosyltransferase
  • Estrone Glucuronyltransferase
  • Morphine Glucuronyltransferase
  • UDP-Glucuronic Acid 3-O-beta-D-Galactosyl-D-Galactose Glucuronosyltransferase
  • p-Nitrophenyl UDP-Glucuronosyltransferase
  • 17 beta Hydroxysteroid UDP Glucuronosyltransferase
  • 4 Nitrophenol UDP Glucuronosyltransferase
  • 7 Hydroxycoumarin UDP Glucuronyltransferase
  • Androsterone UDP Glucuronosyltransferase
  • Bilirubin UDP Glucuronyltransferase
  • Estrogen UDP Glucuronosyltransferase
  • Glucuronyltransferase, 7-Hydroxycoumarin UDP
  • Glucuronyltransferase, Estrone
  • Glucuronyltransferase, Morphine
  • UDP Glucuronic Acid 3 O beta D Galactosyl D Galactose Glucuronosyltransferase
  • UDP Glucuronyltransferase, 7-Hydroxycoumarin
  • UDP-Glucuronosyltransferase, 17 beta-Hydroxysteroid
  • UDP-Glucuronosyltransferase, Androsterone
  • UDP-Glucuronosyltransferase, Estrogen
  • UDP-Glucuronosyltransferase, p-Nitrophenyl
  • UDP-Glucuronyltransferase, Bilirubin
  • p Nitrophenyl UDP Glucuronosyltransferase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic: consider also CRIGLER-NAJJAR SYNDROME & coord with BILIRUBIN /metab (NIM)

MeSH Record

History Note

92; was UDP GLUCURONOSYLTRANSFERASE 1973-91 (see under HEXOSYLTRANSFERASES 1975-76, Prov 1973-74)

MeSH Record

Previous Indexing

  • Hexosyltransferases (1972-1973)
  • Transferases (1966-1971)

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.400w.450w.480w

AMA Style

References

  1. National Library of Medicine. Glucuronosyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D014453. http://id.nlm.nih.gov/mesh/2026/D014453
  2. Glucuronosyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Glucuronosyltransferase
  3. Glucuronosyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q419543