Chemicals and Drugs

Integrin alphaV

An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

10 entry terms
  • Antigens, CD51
  • CD51 Antigen
  • CD51 Antigens
  • Integrin alpha V
  • alpha(V) Integrin
  • alphav Integrin
  • Antigen, CD51
  • Integrin, alphav
  • alpha V, Integrin
  • alphaV, Integrin

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

"V" in alphaV is the letter not the roman numeral

MeSH Record

History Note

2003; use INTEGRIN ALPHAV (NM) 1994-2002

MeSH Record

Previous Indexing

  • Antigens, CD (1994-2002)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Integrin alphaV. Medical Subject Headings (MeSH). 2026. Unique ID D039564. http://id.nlm.nih.gov/mesh/2026/D039564
  2. Integrin alphaV. In: Wikipedia. https://en.wikipedia.org/wiki/Integrin_alpha_V
  3. Integrin alphaV. In: Wikidata. https://www.wikidata.org/wiki/Q21107757