Chemicals and Drugs

Medigoxin

A semisynthetic digitalis glycoside with the general properties of DIGOXIN but more rapid onset of action. Its cardiotonic action is prolonged by its demethylation to DIGOXIN in the liver. It has been used in the treatment of congestive heart failure (HEART FAILURE).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A semisynthetic digitalis glycoside with the general properties of DIGOXIN but more rapid onset of action. Its cardiotonic action is prolonged by its demethylation to DIGOXIN in the liver. It has been used in the treatment of congestive heart failure (HEART FAILURE).

Chemical Identity

Chemical Information

Molecular Formula
C42H66O14
Molecular Weight
795.0 g/mol
CAS Registry No.
30685-43-9
IUPAC Name
3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-3-[(2R,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-methoxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
InChIKey
IYJMSDVSVHDVGT-PEQKVOOWSA-N
SMILES
C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)OC
MeSH Unique ID
D008520
Source
PubChem CID 443946

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 4'''-O-Methyldigoxin
  • Metildigoxin
  • beta-Methyldigoxin
  • 4''' O Methyldigoxin
  • beta Methyldigoxin
  • Bemecor
  • Lanirapid
  • Lanitop
  • Medixin
  • Methyldigoxin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under DIGOXIN 1979-90

MeSH Record

Previous Indexing

  • Digoxin (1966-1978)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.155.580w.130.500.436w.500w
  2. D04w.210.500w.155.580w.130.688w.500w
  3. D09w.408w.180w.261.436w.500w

AMA Style

References

  1. National Library of Medicine. Medigoxin. Medical Subject Headings (MeSH). 2026. Unique ID D008520. http://id.nlm.nih.gov/mesh/2026/D008520
  2. Medigoxin. In: Wikipedia. https://en.wikipedia.org/wiki/Metildigoxin
  3. Medigoxin. In: Wikidata. https://www.wikidata.org/wiki/Q550017
  4. Medigoxin. In: PubChem Compound. CID 443946. https://pubchem.ncbi.nlm.nih.gov/compound/443946